The Office of Life, Justice & Advocacy works to teach respect for all human life from conception to natural death, to organize for its protection and to encourage and enable programs to care for and meet the needs of pregnant women, children, persons with disabilities, those who are sick or dying, all who have been involved in abortion, refugees and immigrants.

The Office exists to lead respect life efforts of the diocese, supervise public policy advocacy, educate for life, peace and justice, and help Catholics in the Diocese of St. Petersburg engage in Ministries of Mercy.

This ministry is supported through gifts to the Catholic Ministry Appeal.